Gout: Understanding Purine Metabolism and How Urate-Lowering Medications Work
Nov, 10 2025
Health and Wellness
Bob Bond
Gout is caused by uric acid crystals forming in joints due to faulty purine metabolism. Understanding how urate-lowering drugs like allopurinol and febuxostat work-and why most patients fail to reach treatment targets-is key to managing this painful condition long-term.