When working with Tadalafil, a phosphodiesterase‑5 (PDE5) inhibitor used to treat erectile dysfunction and benign prostatic hyperplasia. Also known as Cialis, it helps men achieve and maintain an erection by increasing blood flow to the penis. This page explains what the drug does, who can use it, and what to watch out for.
PDE5 inhibitor, a class of medicines that relax smooth muscle in the penis and improve blood circulation includes Tadalafil, Sildenafil, and Vardenafil. All three share the same basic mechanism but differ in timing, duration, and dosing. For instance, Tadalafil’s effect can last up to 36 hours, which is why many call it the “weekend pill.” This longer window gives users more flexibility compared to the shorter‑acting Sildenafil, the original ED medication often known by the brand name Viagra.
The main condition Tadalafil treats is erectile dysfunction, the inability to achieve or maintain a satisfactory erection for sexual activity. It’s also approved for benign prostatic hyperplasia (BPH), a non‑cancerous enlargement of the prostate that causes urinary symptoms. By relaxing smooth muscle in the prostate and bladder neck, Tadalafil can improve urine flow and reduce nighttime trips to the bathroom.
First, dosage matters. The typical starting dose for ED is 10 mg taken before sexual activity, with a possible increase to 20 mg or decrease to 5 mg based on tolerance. For daily use or BPH, a lower dose of 2.5 mg or 5 mg taken at the same time each day is common. Always follow the prescribing doctor’s advice; taking more won’t improve performance but can raise the risk of side effects.
Side effects are usually mild. The most common include headache, flushing, upset stomach, back pain, and muscle aches. These usually fade after a few days. Rarely, users experience vision changes or priapism (an erection lasting longer than 4 hours), which requires immediate medical attention. Knowing the signs early can prevent complications.
Drug interactions are a critical safety point. Tadalafil should never be combined with nitrates (often prescribed for chest pain) because the pair can cause a dangerous drop in blood pressure. Alpha‑blockers used for prostate or hypertension issues also need careful timing to avoid similar drops. Always list all medications to your doctor, including over‑the‑counter supplements.
Age and health status influence how Tadalafil works. Older men or those with heart disease may experience stronger side effects and should start at a lower dose. The drug does not cure underlying vascular problems; it simply helps the body use existing blood flow more effectively. Lifestyle changes—exercise, healthy eating, quitting smoking—can enhance results and overall sexual health.
Cost and access are practical concerns. Generic Tadalafil is widely available and typically cheaper than the brand name Cialis. Prices vary by pharmacy and region, so comparing options can save money. When buying online, use reputable pharmacies that require a prescription and display a valid pharmacy license.
Finally, remember that Tadalafil is part of a broader sexual‑health toolkit. Counseling, relationship communication, and addressing psychological factors often boost success more than medication alone. Combining therapy with the right dose of Tadalafil can lead to lasting improvement.
Below you’ll find a collection of articles that dive deeper into each of these topics—dose guides, side‑effect management, interaction warnings, and comparisons with other ED treatments. Browse the list to get practical tips and detailed insights that fit your situation.